Our Scientific Contributions

Explore our latest research findings and scientific contributions, showcasing our commitment to advancing knowledge and innovation.

Publications 2026

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A Reproducible Workflow for Macrophage Membrane Isolation and Nanocore Selection Toward Bioinspired Nanoparticles Targeting Immunologically Cold Tumors
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Heme oxygenase 1 inhibitor discovery and formulation into nanostructured lipid carriers as potent and selective treatment against triple negative metastatic breast cancer. International Journal of Pharmaceutics, 668, 124997
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Engineering mannose-functionalized nanostructured lipid carriers by sequential design using hybrid artificial intelligence tools. Drug Delivery and Translational Research, 15 (1), 343-354
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Exploring the Role of LLMs like ChatGPT in Pharmacy Education for Supporting Students’ Therapeutic Decision-Making. American Journal of Pharmaceutical Education, 101462
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Chitosan-aloe vera scaffolds with tuned extracellular vesicles and histatin-5 display osteogenic and anti-biofilm activities. International Journal of Pharmaceutics 676, 125592
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Micelle-to-Gel: Thermosensitive intra-articular hydrogels for osteoarthritis management. Journal of Controlled Release 381, 113639
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Combining antibacterial and wound healing features: xanthan gum/guar gum 3D-printed scaffold tuned with hydroxypropyl-β-cyclodextrin/thymol and Zn2+. Carbohydrate Polymers 351, 123069
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Paracrine activity of Smurf1-silenced mesenchymal stem cells enhances bone regeneration and reduces bone loss in postmenopausal osteoporosis. Stem Cell Research & Therapy, 16, 50
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Combining antibacterial and wound healing features: Xanthan gum/guar gum 3D-printed scaffold tuned with hydroxypropyl-β-cyclodextrin/thymol and Zn2+. Carbohydrate Polymers. 351, 123069
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Fighting antibiotic resistance in the local management of bovine mastitis. Biomedicine and Pharmacotherapy, Vol. 170
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Harnessing extracellular vesicle membrane for gene therapy: EVs-biomimetic nanoparticles. Colloids and Surfaces B: Biointerfaces, Vol. 239
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Magnetic-driven Interleukin-4 internalization promotes magnetic nanoparticle morphology and size-dependent macrophage polarization. Journal of colloid and interface science, Vol. 655, pp. 286-295
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Xanthan gum/Guar gum-based 3D-printed scaffolds for wound healing: production, characterization, and biocompatibility screening. Carbohydrate Polymer Technologies and Applications, Vol. 7
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Modulating osteoclasts with nanoparticles: A path for osteoporosis management? Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology, Vol. 15, Núm. 4
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Rationalized design to explore the full potential of PLGA microspheres as drug delivery systems. Drug delivery, Vol. 30, Núm. 1
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Vancomycin-Loaded 3D-Printed Polylactic Acid–Hydroxyapatite Scaffolds for Bone Tissue Engineering. Polymers, Vol. 15, Núm. 21
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Nanoparticle-mediated selective Sfrp-1 silencing enhances bone density in osteoporotic mice. Journal of Nanobiotechnology, Vol. 20, Núm. 1
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New local ganirelix sustained release therapy for uterine leiomyoma. Evaluation in a preclinical organ model. Biomedicine and Pharmacotherapy, Vol. 156
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Pitavastatin loaded nanoparticles: A suitable ophthalmic treatment for Acanthamoeba Keratitis inducing cell death and autophagy in Acanthamoeba polyphaga. European Journal of Pharmaceutics and Biopharmaceutics, Vol. 180
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Screening strategies for surface modification of lipid-polymer hybrid nanoparticles. International Journal of Pharmaceutics, Vol. 624
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Sublingual Boosting with a Novel Mucoadhesive Thermogelling Hydrogel Following Parenteral CAF01 Priming as a Strategy Against Chlamydia trachomatis. Advanced Healthcare Materials, Vol. 11, Núm. 11
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Targeting joint inflammation for osteoarthritis management through stimulus-sensitive hyaluronic acid based intra-articular hydrogels. Materials Science and Engineering C, Vol. 128
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The bone regeneration capacity of bmp-2 + mmp-10 loaded scaffolds depends on the tissue status. Pharmaceutics, Vol. 13, Núm. 7
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The three NADH dehydrogenases of Pseudomonas aeruginosa: Their roles in energy metabolism and links to virulence. PLoS ONE, Vol. 16, Núm. 2
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A traffic light system to maximize carbohydrate cryoprotectants’ effectivity in nanostructured lipid carriers’ lyophilization. Pharmaceutics, Vol. 13, Núm. 9
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Design of novel orotransmucosal vaccine-delivery platforms using artificial intelligence. European Journal of Pharmaceutics and Biopharmaceutics, Vol. 159
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Evaluation of human umbilical vein endothelial cells growth onto heparin-modified electrospun vascular grafts. International Journal of Biological Macromolecules, Vol. 179
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Tailor-made oligonucleotide-loaded lipid-polymer nanosystems designed for bone gene therapy. Drug Delivery and Translational Research, Vol. 11, Núm. 2
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Tailored hydrogels as delivery platforms for conditioned medium from mesenchymal stem cells in a model of acute colitis in mice. Pharmaceutics, Vol. 13, Núm. 8
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Targeting joint inflammation for osteoarthritis management through stimulus-sensitive hyaluronic acid based intra-articular hydrogels. Materials Science and Engineering C, Vol. 128
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Amino-functionalized polymers by gamma radiation and their influence on macrophage polarization. Reactive and Functional Polymers, Vol. 151
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In Vitro and Ex Vivo Evaluation of Nepafenac-Based Cyclodextrin Microparticles for Treatment of Eye Inflammation. Nanomaterials, Vol. 10, Núm. 4
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Influence of the carbon source on the properties of poly-(3)-hydroxybutyrate produced by Paraburkholderia xenovorans LB400 and its electrospun fibers. International Journal of Biological Macromolecules, Vol. 152
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Micelle-nanogel platform for ferulic acid ocular delivery. International Journal of Pharmaceutics, Vol. 576
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New tools to design smart thermosensitive hydrogels for protein rectal delivery in IBD. Materials Science and Engineering C, Vol. 106
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Rifabutin-loaded nanostructured lipid carriers as a tool in oral anti-mycobacterial treatment of crohn’s disease. Nanomaterials, Vol. 10, Núm. 11
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In vitro evaluation of anti-fibrotic effects of select cytokines for vocal fold scar treatment. Journal of Biomedical Materials Research – Part B Applied Biomaterials, Vol. 107, Núm. 4
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Incorporation of a silicon-based polymer to PEG-DA templated hydrogel scaffolds for bioactivity and osteoinductivity. Acta Biomaterialia, Vol. 99
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Mesenchymal stem cells in homeostasis and systemic diseases: Hypothesis, evidences, and therapeutic opportunities. International Journal of Molecular Sciences, Vol. 20, Núm. 15
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Refined assessment of the impact of cell shape on human mesenchymal stem cell differentiation in 3D contexts. Acta Biomaterialia, Vol. 87
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Toward zonally tailored scaffolds for osteochondral differentiation of synovial mesenchymal stem cells. Journal of Biomedical Materials Research – Part B Applied Biomaterials, Vol. 107, Núm. 6
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A Bioengineered In Vitro Osteoarthritis Model with Tunable Inflammatory Environments Indicates Context-Dependent Therapeutic Potential of Human Mesenchymal Stem Cells. Regenerative Engineering and Translational Medicine, Vol. 5, Núm. 3
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nandamide-nanoformulation obtained by electrospraying for cardiovascular therapy. International Journal of Pharmaceutics, Vol. 566
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Current stage of marine ceramic grafts for 3D bone tissue regeneration. Marine Drugs, Vol. 17, Núm. 8
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Effect of Poly(sophorolipid) Functionalization on Human Mesenchymal Stem Cell Osteogenesis and Immunomodulation. ACS Applied Bio Materials, Vol. 2, Núm. 1
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Elucidating the role of graft compliance mismatch on intimal hyperplasia using an ex vivo organ culture model. Acta Biomaterialia, Vol. 89